BCL3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human BCL3 wild-type allele is located within 19q13.1-q13.2 and is approximately 11 kb in length. This allele, which encodes B-cell lymphoma 3-encoded protein, plays a role in the modulation of transcription. In some cases of B-cell leukemia, the gene is involved a translocation t(14;19)(q32;q13.1), which embeds this gene in the immunoglobulin-alpha gene locus.

**Synonyms:** - B-Cell CLL/Lymphoma 3 Gene - B-Cell Leukemia/Lymphoma 3 Gene - BCL3 - BCL3 Transcription Coactivator wt Allele - BCL3, Transcription Coactivator Gene - BCL4 - D19S38