RUNX1T1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RUNX1T1 wild-type allele is located in the vicinity of 8q22 and is approximately 136 kb in length. This allele, which encodes protein CBFA2T1, may be involved in the regulation of transcription. Acute myeloid leukemia of the M2 subtype is associated with a translocation t(8;21)(q22;q22), which fuses this gene to the RUNX1 gene.

**Synonyms:** - AML1T1 - Acute Myelogenous Leukemia 1 Translocation 1, Cyclin-D Related Gene - CBFA2T1 - CBFA2T1 Gene - CDR - Core-Binding Factor, Runt Domain, Alpha Subunit 2; Translocated To, 1; Cyclin D-Related Gene - ETO - MGC2796 - MTG8 - Myeloid Translocation Gene on 8q22 - Myeloid Translocation Gene on 8q22 Gene - RUNX1 Partner Transcriptional Co-Repressor 1 wt Allele - RUNX1 Translocation Partner 1 Gene - RUNX1, Translocated To, 1 Gene - RUNX1T1 - Runt-Related Transcription Factor 1, Translocated to, 1 Gene - Runt-Related Transcription Factor 1; Translocated to, 1 (Cyclin D-Related) Gene - ZMYND2