RRAS2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RRAS2 wild-type allele is located in the vicinity of 11p15.2 and is approximately 80 kb in length. This allele, which encodes Ras-related protein R-Ras2, may play a role in both phosphatidylinositol-mediated signal transduction and nuclear factor kappa B complex pathway attenuation. A point mutation in the gene is associated with ovarian cancer.

**Synonyms:** - NS12 - RAS Related 2 wt Allele - Related RAS Viral (r-ras) Oncogene Homolog 2 Gene - Related RAS Viral Oncogene Homolog 2 Gene - TC21 - Teratocarcinoma Oncogene TC21 Gene