Gastric Mucosa-Associated Lymphoid Tissue Lymphoma

**Semantic type:** Neoplastic Process

**Definition:** A low-grade, indolent B-cell lymphoma that arises from the gastric mucosa and is usually associated with Helicobacter pylori infection. Morphologically it is characterized by a dense mucosal atypical lymphocytic (centrocyte-like cell) infiltrate with often prominent lymphoepithelial lesions and plasmacytic differentiation. Approximately 40% of gastric MALT lymphomas carry the t(11;18)(q21;q21). Such cases are resistant to Helicobacter pylori therapy.

**Synonyms:** - Gastric MALT Lymphoma - Gastric MALToma - MALT Lymphoma of Stomach - MALT Lymphoma of the Stomach - MALToma of Stomach - MALToma of the Stomach - Primary Gastric B-Cell MALT Lymphoma - Primary Gastric MALT Lymphoma - Primary MALT Lymphoma of Stomach - Primary MALT Lymphoma of the Stomach