SMAD3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SMAD3 wild-type allele is located in the vicinity of 15q22.33 and is approximately 130 kb in length. This allele, which encodes mothers against decapentaplegic homolog 3 protein, plays a role in the transcriptional regulation of the cellular response to transforming growth factor-beta.

**Synonyms:** - HSPC193 - HsT17436 - JV15-2 - LDS1C - LDS3 - MAD, Mothers Against Decapentaplegic Homolog 3 (Drosophila) Gene - MAD, Mothers Against Decapentaplegic Homolog 3 Gene - MADH3 - Mothers Against Decapentaplegic, Drosophila, Homolog of, 3 Gene - SMAD Family Member 3 wt Allele - SMAD, Mothers Against DPP Homolog 3 (Drosophila) Gene