SMAD4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SMAD4 wild-type allele is located in the vicinity of 18q21.1 and is approximately 50 kb in length. This allele, which encodes mothers against decapentaplegic homolog 4 protein, plays a role in the modulation of signal transduction that is mediated by cytokines in the transforming growth factor beta superfamily.

**Synonyms:** - DPC4 - Deleted in Pancreatic Carcinoma 4 Gene - Deleted in Pancreatic Carcinoma Locus 4 Gene - Deletion Target in Pancreatic Carcinoma 4 Gene - JIP - MAD Homolog 4 Gene - MADD, Mothers Against Decapentaplegic Homolog 4 (Drosophila) Gene - MADH4 - MADH4 Gene - MYHRS - Mothers Against Decapentaplegic Homolog 4 Gene - Mothers Against Decapentaplegic, Drosophila, Homolog, 4 Gene - SMAD Family Member 4 wt Allele - SMAD, Mothers Against DPP Homolog 4 (Drosophila) Gene - SMAD4/DPC4 Gene