TAB1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TAB1 wild-type allele is located in the vicinity of 22q13.1 and is approximately 38 kb in length. This allele, which encodes TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, is involved in various intracellular signaling pathways, including those induced by tumor growth factor-beta, interleukin 1, and Wnt proteins.

**Synonyms:** - 3'-Tab1 - MAP3K7IP1 - Mitogen-Activated Protein Kinase Kinase Kinase 7 Interacting Protein 1 Gene - TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 1 wt Allele