ETS1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ETS1 wild-type allele is located in the vicinity of 11q23 and is approximately 64 kb in length. This allele, which encodes protein C-ets-1, plays a role in the modulation of transcription by RNA polymerase II. Chromosomal aberrations leading to rearrangement or elevated expression of the gene are a factor in a variety of leukemias.

**Synonyms:** - ETS - ETS Proto-Oncogene 1, Transcription Factor wt Allele - ETS-1 - ETS1 - ETS1 Proto-Oncogene - EWSR2 - c-ets-1 - p54 - v-ETS Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) Gene - v-ets Avian Erythroblastosis Virus E26 Oncogene Homolog 1 Gene