FLI1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human FLI1 wild-type allele is located within 11q24.1-q24.3 and is approximately 118 kb in length. This allele, which encodes Friend leukemia integration 1 transcription factor protein, plays a role in the activation of transcription by RNA polymerase II. Ewing sarcoma is linked to the chromosomal translocation t(11;22)(q24;q12) of the EWSR1 gene and the FLI1 gene.

**Synonyms:** - BDPLT21 - EWSR2 - Ewing Sarcoma Breakpoint Region 2 - FLI-1 - Friend Leukemia Virus Integration 1 wt Allele - SIC-1