MAPK8 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MAPK8 wild-type allele is located in the vicinity of 10q11.22 and is approximately 133 kb in length. This allele, which encodes mitogen-activated protein kinase 8 protein, plays a role in the induction of programmed cell death mediated by both tumor necrosis factor-alpha and ultraviolet radiation.

**Synonyms:** - JNK - JNK1 - JNK1A2 - JNK21B1/2 - MAP Kinase 8 Gene - Mitogen-Activated Protein Kinase 8 wt Allele - PRKM8 - SAPK1