GLI3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GLI3 wild-type allele is located in the vicinity of 7p13 and is approximately 272 kb in length. This allele, which encodes zinc finger protein GLI3, plays a role in the regulation of sonic hedgehog-dependent transcription of specific genes during the development of multiple organ systems. This gene is the site of a mutation that is linked to Greig cephalopolysyndactyly syndrome.

**Synonyms:** - ACLS - GCPS - GCPS-190 - GLI-Kruppel Family Member 3 - GLI-Kruppel Family Member GLI3 (Greig Cephalopolysyndactyly Syndrome) wt Allele - GLI3FL - PAP-A - PAPA - PAPA1 - PAPB - PHS - PPDIV