NKX3-1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NKX3-1 wild-type allele is located in the vicinity of 8p21 and is approximately 4 kb in length. This allele, which encodes homeobox protein Nkx-3.1, plays a role in the suppression of transcription by RNA polymerase II, the proliferation of glandular epithelium and the development of ducts in the prostate.

**Synonyms:** - NK3 Transcription Factor Related, Locus 1 (Drosophila) wt Allele - NKX3-1 - NKX3.1 - NKX3A