KMT2A wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KMT2A wild-type allele is located in the vicinity of 11q23 and is approximately 89 kb in length. This allele, which encodes histone-lysine N-methyltransferase 2A protein, is involved in the modulation of transcription by RNA Polymerase II. Several acute leukemias are associated with translocations of the gene.

**Synonyms:** - ALL-1 - ALL1 - CXXC7 - HRX - HTRX - HTRX1 - Lysine (K)-Specific Methyltransferase 2A Gene - Lysine Methyltransferase 2A wt Allele - MLL - MLL wt Allele - MLL1 - MLL1A - Mixed Lineage Leukemia Gene - Myeloid-Lymphoid Leukemia Gene - Myeloid/Lymphoid Leukemia Gene - Myeloid/Lymphoid or Mixed Lineage Leukemia Gene - Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax (Drosophila) Homolog) Gene - Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila) Gene - TRX1 - Trithorax, Drosophila, Homolog of Gene - WDSTS - hCG_1732268