MLLT3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MLLT3 wild-type allele is located in the vicinity of 9p22 and is approximately 281 kb in length. This allele, which encodes protein AF-9, plays a role in modulation of transcription by RNA polymerase II (Gene Ontology/GO). Acute nonlymphocytic leukemia is associated with the translocation t(9;11)(p22;q23) of this gene and the MLL gene.

**Synonyms:** - AF-9 - AF9 - FLJ2035 - MLLT3 - MLLT3 Super Elongation Complex Subunit wt Allele - Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog); Translocated To, 3 Gene - Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated to, 3 Gene - Myeloid/Lymphoid or Mixed-Lineage Leukemia; Translocated To 3 Gene - Myeloid/Lymphoid or Mixed-Lineage Leukemia; Translocated To, 3 Gene - YEATS3