MYCN wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MYCN wild-type allele is located in the vicinity of 2p24.1 and is approximately 6 kb in length. This allele, which encodes N-myc proto-oncogene protein, is involved in the modulation of transcription by RNA polymerase II. The gene is expressed at elevated levels in neuroblastoma, retinoblastoma, small cell lung carcinoma and astrocytoma.

**Synonyms:** - Avian Myelocytomatosis Viral-Related Oncogene, Neuroblastoma-Derived Gene - BHLHE37 - MODED - MYCN - MYCN Proto-Oncogene, bHLH Transcription Factor wt Allele - MYCNOT - MYCNsORF - MYCNsPEP - N-MYC - N-myc - NMYC - NMYC Oncogene Gene - Neuroblastoma MYC Oncogene Gene - Neuroblastoma-Derived V-Myc Avian Myelocytomatosis Viral Related Oncogene Gene - ODED - Oncogene NMYC Gene - V-Myc Avian Myelocytomatosis Viral Oncogene Neuroblastoma Derived Homolog Gene - V-Myc Avian Myelocytomatosis Viral-Related Oncogene, Neuroblastoma-Derived Gene - bHLHe37 - v-MYC Myelocytomatosis Viral Related Oncogene, Neuroblastoma Derived (Avian) Gene