EIF2B1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human EIF2B1 wild-type allele is located in the vicinity of 12q24.31 and is approximately 13 kb in length. This allele, which encodes translation initiation factor eIF-2B subunit alpha protein, is involved in the regulation of protein elongation. Point mutations in the gene are linked to leukoencephalopathy with vanishing white matter.

**Synonyms:** - EIF-2Balpha - EIF2BA - Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa wt Allele