EIF2B5 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human EIF2B5 wild-type allele is located in the vicinity of 3q27.1 and is approximately 10 kb in length. This allele, which encodes translation initiation factor eIF-2B subunit epsilon protein, is involved in the regulation of messenger RNA translation. Genetic mutations in the allele are linked to Cree leukoencephalopathy, leukoencephalopathy with vanishing white matter and ovarioleukodystrophy.

**Synonyms:** - CACH - CLE - EIF2BE - EIF2Bepsilon - Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa wt Allele - LVWM