Brivanib Alaninate

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** The alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression.

**Synonyms:** - BMS 582664 - BMS-582664 - BRIVANIB ALANINATE - Brivanib L-Alanine Ester - brivanib alaninate