Vascular Endothelial Growth Factor Antisense Oligonucleotide

**Semantic type:** Nucleic Acid, Nucleoside, or Nucleotide|Pharmacologic Substance

**Definition:** An antisense oligonucleotide with potential antiangiogenesis activity. Vascular endothelial growth factor (VEGF) antisense oligonucleotide binds directly to binds VEGF A/C/D mRNA, leading to mRNA degradation and the inhibition of VEGF A-mediated angiogenesis and VEGF C/D-mediated lymphangiogenesis.

**Synonyms:** - VEGF-AS - VEGF-AS - Veglin - vascular endothelial growth factor-antisense oligonucleotide