Luminal A Breast Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** A biologic subset of breast carcinoma defined by high expression of genes characteristic of luminal epithelial cells, including estrogen receptor (ER), estrogen regulated protein LIV-1, and the transcription factors hepatocyte nuclear factor 3, HNF3A, XBP1, and GATA 3. This subtype of breast cancer is associated with a good prognosis.

**Synonyms:** - Luminal A - Luminal A Breast Cancer - Luminal A Breast Cancer - Luminal A Estrogen Receptor Positive Subtype of Breast Carcinoma - Luminal A Subtype of Breast Carcinoma