Luminal B Breast Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** A biologic subset of breast carcinoma defined by low to moderate expression of genes characteristic of luminal epithelial cells including estrogen receptor (ER), and high expression of GGH, LAPTM4B, and CCNE1. This subtype of breast cancer is associated with a good prognosis, although not as favorable as the luminal A subtype.

**Synonyms:** - Luminal B - Luminal B Breast Cancer - Luminal B Estrogen Receptor Positive Subtype of Breast Carcinoma - Luminal B Subtype of Breast Carcinoma