ITGAV wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ITGAV wild-type allele is located within 2q31-q32 and is approximately 90 kb in length. This allele, which encodes integrin alpha-V protein, is involved in cellular adhesion and signal transduction. Variant alleles are associated with several types of human cancer and play a role in metastasis.

**Synonyms:** - CD51 - CD51 Antigen Gene - Integrin, Alpha V (Vitronectin receptor, Alpha Polypeptide, Antigen CD51) Gene - Integrin, Alpha V wt Allele - Integrin, Alpha-V Gene - MSK8 - VNRA - VTNR - Vitronectin Receptor, Alpha Polypeptide Gene