Bone Osteosarcoma

**Semantic type:** Neoplastic Process

**Definition:** A usually aggressive malignant bone-forming mesenchymal neoplasm arising from the bone. It may arise de novo or from a pre-existing lesion of the bone. Pain and a palpable mass are the most frequent clinical sign and symptom. It may spread to other anatomic sites, particularly the lungs.

**Synonyms:** - Osteosarcoma of Bone