ITGB5 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ITGB5 wild-type allele is located in the vicinity of 3q21.2 and is approximately 124 kb in length. This allele, which encodes integrin beta-5 protein, is involved in cell-extracellular adhesion, intercellular adhesion and receptor-mediated signal transduction. Variant alleles are associated with several cancers such as glial tumors and gastric carcinomas.

**Synonyms:** - Integrin, Beta 5 wt Allele - Integrin, Beta-5 Gene