Columnar Cell Change of the Breast

**Semantic type:** Neoplastic Process

**Definition:** A columnar cell lesion characterized by the presence of enlarged terminal ductal lobular units with dilated acini. The acini are lined by one or two layers of columnar epithelial cells. Apical cytoplasmic snouts may be present, but they are not prominent. Secretions may be present in the lumina of the dilated acini.

**Synonyms:** - Blunt Duct Adenosis of Breast - Blunt Duct Adenosis of the Breast - Breast Blunt Duct Adenosis - Breast Columnar Cell Change - CCC - Columnar Cell Change - Columnar Cell Change of Breast