FANCM wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human FANCM wild-type allele is located in the vicinity of 14q21.3 and is approximately 65 kb in length. This allele, which encodes Fanconi anemia group M protein, is involved in a specific protein ubiquination that is necessary for DNA repair. Cytogenetic aberrations in the FANCM gene are both a cause of Fanconi anemia and a predisposing factor in the development of malignancies.

**Synonyms:** - FA Complementation Group M wt Allele - FAAP250 - Fanconi Anemia Complementation Group M Gene - Fanconi Anemia, Complementation Group M Gene - Fanconi Anemia-Associated Polypeptide, 250-kD Gene - KIAA1596