KDSR wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KDSR wild-type allele is located in the vicinity of 18q21.3 and is approximately 37 kb in length. This allele, which encodes 3-ketodihydrosphingosine reductase protein, is involved in sphingolipid biosynthesis. Translocation t(2;18)(p11;q21) of KDSR with an Ig J kappa chain region is a cause of follicular lymphoma.

**Synonyms:** - 3-Ketodihydrosphingosine Reductase wt Allele - DHSR - FLJ36555 - FLJ92680 - FVT1 - Follicular Lymphoma Variant Translocation 1 Gene - Follicular-Variant-Translocation Gene - SDR35C1