Clear Cell Odontogenic Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** A usually aggressive malignant neoplasm arising from tooth-forming tissues. It more often affects older females and more frequently occurs in the mandible. It is characterized by the presence of malignant epithelial cells with clear cytoplasm and a fibrotic stroma formation. It may recur and metastasize. Metastases may occur in the lymph nodes, lungs, and bones. Treatment of choice is resection with clean margins.

**Synonyms:** - Clear Cell Ameloblastoma - Clear Cell Odontogenic Tumor - Clear cell odontogenic carcinoma - Clear cell odontogenic tumor