KMT2D wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KMT2D wild-type allele is located within 12q12-q14 and is approximately 36 kb in length. This allele, which encodes histone-lysine N-methyltransferase 2D protein, is involved in an estrogen receptor alpha co-activation complex that is necessary for estrogen-induced gene expression.

**Synonyms:** - AAD10 - ALR - CAGL114 - KABUK1 - KMS - Lysine (K)-Specific Methyltransferase 2D Gene - Lysine Methyltransferase 2D wt Allele - MLL2 - MLL4 - Myeloid/Lymphoid or Mixed-Lineage Leukemia 2 Gene - TNRC21