AFDN wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human AFDN wild-type allele is located in the vicinity of 6q27 and is approximately 145 kb in length. This allele, which encodes afadin protein, is involved in the mediation of cell to cell adhesion. The gene can be involved in a translocation with the KMT2A (MLL) gene, t(6;11)(q27;q23), which is associated with some acute leukemias.

**Synonyms:** - AF-6 - AF6 - AFADIN - ALL1-Fused Gene From Chromosome 6 - Afadin, Adherens Junction Formation Factor wt Allele - CANOE, Drosophila, Homolog of Gene - FLJ34371 - MLLT4 - Mixed-Lineage Leukemia, Translocated to, 4 Gene - Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated to, 4 Gene - Myeloid/Lymphoid or Mixed-Lineage Leukemia, Translocated to, 4 Gene - RP3-431P23.3 - l-afadin