MANF wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MANF wild-type allele is located in the vicinity of 3p21.1 and is approximately 4 kb in length. This allele, which encodes mesencephalic astrocyte-derived neurotrophic factor protein, plays a role in both the modulation of GABA neurotransmission and the mediation of dopaminergic neuron survival.

**Synonyms:** - ARMET - ARP - Arginine-Rich Mutated In Early Stage Tumors Gene - MGC142148 - MGC142150 - Mesencephalic Astrocyte-Derived Neurotrophic Factor wt Allele