TUSC3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TUSC3 wild-type allele is located within 8p22 and is approximately 224 kb in length. This allele, which encodes tumor suppressor candidate 3 protein, is involved in the N-glycosylation of proteins. Down-regulation of TUSC3 gene expression is associated with several forms of cancer such as ovarian carcinomas.

**Synonyms:** - D8S1992 - M33 - MGC13453 - MRT22 - MRT7 - N33 - OST3A - Oligosaccharyltransferase 3 Homolog A (S. cerevisiae) Gene - Tumor Suppressor Candidate 3 wt Allele