BRINP1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human BRINP1 wild-type allele is located within 9q32-q33 and is approximately 203 kb in length. This allele, which encodes BMP/retinoic acid-inducible neural-specific protein 1, is involved in the modulation of cellular proliferation, the inhibition of the G1/S transition of the cell cycle, the mediation of non-apoptotic cell death and the regulation of the expression of components of the fibrinolysis pathway. Hypermethylation-based silencing or loss of homozygosity of the gene occurs in many cases of bladder cancer.

**Synonyms:** - BA574M5.1 - BA574M5.1 (Deleted In Bladder Cancer Chromosome Region Candidate 1 (IB3089A)) Gene - BMP/Retinoic Acid Inducible Neural Specific 1 wt Allele - DBC1 - DBCCR1 - Deleted in Bladder Cancer 1 Gene - Deleted in Bladder Cancer Chromosome Region Candidate 1 Gene - FAM5A - IB3089A