SOD1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SOD1 wild-type allele is located within 21q22 and is approximately 9 kb in length. This allele, which encodes superoxide dismutase [Cu-Zn] protein, is involved in the conversion of superoxide radicals to molecular oxygen and hydrogen peroxide. Certain allelic variants of the SOD1 gene cause Amyotrophic Lateral Sclerosis.

**Synonyms:** - ALS - ALS1 - IPOA - SOD - Superoxide Dismutase 1, Soluble (Amyotrophic Lateral Sclerosis 1 (Adult)) wt Allele