Invasive Breast Lobular Carcinoma, Signet Ring Variant

**Semantic type:** Neoplastic Process

**Definition:** An invasive lobular carcinoma characterized by the presence of malignant epithelial cells with large intracytoplasmic lumina that cause displacement of the nuclei towards one pole of the cells.

**Synonyms:** - Invasive Breast Lobular Carcinoma, Signet-Ring Variant - Invasive Lobular Breast Carcinoma, Signet Ring Variant - Signet Ring Cell Lobular Breast Carcinoma