GPX1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GPX1 wild-type allele is located in the vicinity of 3p21.3 and is approximately 12 kb in length. This allele, which encodes glutathione peroxidase 1 protein, is involved in detoxification of hydrogen peroxide. Variant alleles of GPX1 are associated with type 2 diabetes mellitus as well as certain types of cancer such as breast, lung and prostate cancer.

**Synonyms:** - GSHPX1 - Glutathione Peroxidase 1 wt Allele - MGC14399 - MGC88245