Gallbladder Sarcomatoid Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** A rare aggressive carcinoma that arises from the gallbladder. It is characterized by the presence of poorly differentiated pleomorphic carcinoma cells admixed with malignant spindle-shaped cells that express epithelial immunohistochemical markers.

**Synonyms:** - GBSC - Gallbladder Undifferentiated Carcinoma, Spindle and Giant Cell Type - Pleomorphic Spindle and Giant Cell Carcinoma of Gallbladder - Pleomorphic Spindle and Giant Cell Carcinoma of the Gallbladder - Undifferentiated Gallbladder Carcinoma, Spindle and Giant Cell Type