Recombinant Interleukin-3

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A recombinant form of interleukin-3, a cytokine produced by activated T-cells and mast cells involved in intercellular communication, hematopoiesis, and inflammation. IL-3 binds and activates specific receptors on hematopoietic cells and in the nervous system, triggering expression of specific genes via the Ras signaling pathway and through Jak2 activation. This agent stimulates the proliferation of pluripotent hematopoietic progenitor cells.

**Synonyms:** - Colony-Stimulating Factor 2 Alpha - Eosinophil-Mast Cell Growth-Factor - Erythrocyte Burst-Promoting Factor - IL-3 - ILE-964 - Interleukin-3 - MCGF - Mast-Cell Colony-Stimulating Factor - Multipotential Colony-Stimulating Factor