Binetrakin

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A recombinant agent chemically identical to or similar to the endogenous cytokine interleukin-4 (IL-4). Produced primarily by activated T-cells, IL-4 binds to and activates its cell-surface receptor, stimulating the proliferation and differentiation of activated B-cells and enhancing their ability to present antigens to T-cells. As a potential immunotherapeutic agent, binetrakin also augments the effects of other cytokines on dendritic cells (DC), cytotoxic T lymphocytes (CTL), and tumor-infiltrating lymphocytes (TIL).

**Synonyms:** - B Cell Proliferating Factor - B-Cell Growth Factor - B-Cell Stimulating Factor - B-Cell Stimulatory Factor 1 - BCGF - BCSF 1 - BINETRAKIN - IL-4 - IL-4 - Interleukin 4 (Human) 129 - Interleukin-4 - Interleukin-4 - MCGF 2 - Mast Cell Growth Factor-2 - RHIL-4 - Recombinant Human IL-4 - SCH 93400 - T-Cell Growth Factor 2