3-Iodotyrosine

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** An intermediate in the production of thyroid hormones and derivative of tyrosine where the carbon at position 3 in the benzyl group has been iodinated by thyroid peroxidase. 3-iodotyrosine (mono-iodotyrosine) can be further iodinated by thyroid peroxidase to form di- and tri-iodo forms. Mono-iodotyrosine can combine with a di-iodotyrosine to form triiodothyronine (T3) and two di-iodotyrosines can combine to form thyroxine (T4).

**Synonyms:** - 3-IODOTYROSINE - 3-Iodo-4-Hydroxyphenylalanine - 3-Iodo-L-Tyrosine - Monoiodotyrosine