RASSF1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RASSF1 wild-type allele is located in the vicinity of 3p21.3 and is approximately 11 kb in length. This allele, which encodes Ras association domain-containing protein 1, is involved in death receptor-dependent apoptosis. Loss or altered expression of the gene is associated with the pathogenesis of a variety of cancers, including lung cancer.

**Synonyms:** - 123F2 - NORE2A - RASSF1A - RDA32 - REH3P21 - Ras Association (RalGDS/AF-6) Domain Family 1 Gene - Ras Association Domain Family Member 1 wt Allele