CARD11 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CARD11 wild-type allele is located within 7p22 and is 138 kb in length. This allele, which encodes caspase recruitment domain-containing protein 11, plays a role in apoptosis regulation and signal transduction. Mutation of the gene is associated with immunodeficiency types 11A and 11B and with B-cell expansion with NFKB and T-cell anergy (BENTA).

**Synonyms:** - BENTA - BIMP3 - CARMA1 - Caspase Recruitment Domain Family Member 11 wt Allele - Caspase Recruitment Domain Family, Member 11 Gene - IMD11 - IMD11A - MGC133069 - PPBL