MALT1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MALT1 wild-type allele is located in the vicinity of 18q21 and is approximately 79 kb in length. This allele, which encodes mucosa associated lymphoid tissue lymphoma translocation gene 1 protein, plays a role in the modulation of the nuclear factor kappa B complex signaling cascade. The gene is involved in a chromosomal translocation t(11;18)(q21;q21) with the BIRC2 gene in mucosa-associated lymphoid tissue lymphomas.

**Synonyms:** - Caspase-Like Protein Gene - DKFZp434L132 - IMD12 - MALT1 Paracaspase wt Allele - MALT1 Protease Gene - MLT - MLT1 - Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 - PCASP1