Pazopanib Hydrochloride

**Semantic type:** Pharmacologic Substance

**Definition:** The hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated.

**Synonyms:** - 5-((4-((2,3-Dimethyl-2h-Indazol-6-Yl)Methylamino)Pyrimidin-2-yl)Amino)-2-Methylbenzenesulfonamide Monohydrochloride - GW 786034B - GW-786034B - GW786034B - PAZOPANIB HYDROCHLORIDE - Pazopater - Votrient - Votrient - pazopanib hydrochloride