Leukotriene B4

**Semantic type:** Biologically Active Substance|Organic Chemical

**Definition:** A leukotriene synthesized from leukotriene A4 by leukotriene A-4 hydrolase in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts. Leukotriene B4 modulates inflammation by promoting neutrophil activation and inducing adhesion, activation, and transendothelial migration of leukocytes.

**Synonyms:** - 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic Acid - LEUKOTRIENE B4 - LTB4