Cystine/Glutamate Transporter Protein

**Semantic type:** Amino Acid, Peptide, or Protein|Receptor

**Definition:** Cystine/glutamate transporter protein (501aa, ~55 kDa) is encoded by the human SLC7A11 gene. This protein is involved in the exchange of anionic amino acids and has a high specificity for anionic forms of cystine and glutamate. The protein has been identified as a method of entry utilized by the Karposi's sarcoma herpesvirus to gain entry into the cell. The virus plays an essential role in the pathogenesis of Karposi's sarcoma and certain types of lymphoma.

**Synonyms:** - Amino Acid Transport System xc- - Calcium Channel Blocker Resistance Protein CCBR1 - Cystine/Glutamate Transporter - SLC7A11 - Solute Carrier Family 7 Member 11 - System Xc(-) Transporter-Related Protein - XCT