Sivifene

**Semantic type:** Pharmacologic Substance

**Definition:** The phenylhydrazone 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone formulated as a topical agent with immunomodulating and potential antineoplastic activities. Applied topically as a gel, sivifene may stimulate a local immune response against human papillomavirus (HPV)-induced cervical intraepithelial neoplasia (CIN).

**Synonyms:** - 4,4'-Dihydroxybenzophenone 2,4-dinitrophenylhydrazone - A-007 - Aryl Hydrazone A-007 Gel - SIVIFENE