Recombinant Thyrotropin Alfa

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A recombinant form of the human anterior pituitary glycoprotein thyroid stimulating hormone (TSH) with use in the diagnostic setting. With an amino acid sequence identical to that of human TSH, thyrotropin alfa binds to TSH receptors on normal thyroid epithelial cells or well-differentiated thyroid cancer cells, stimulating iodine uptake and organification, synthesis and secretion of thyroglobulin (Tg), triiodothyronine (T3), and thyroxine (T4).

**Synonyms:** - Recombinant TSH Alpha - Recombinant Thyrotropin Alpha - THYROTROPIN ALFA - TSH-alpha - Thyrogen - Thyrogen - Thyroid Stimulating Hormone Alpha - Thyrotropin Alfa - thyrotropin alfa