Lidocaine

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia.

**Synonyms:** - .omega.-Diethylamino-2,6-dimethylacetanilide - 2-(Diethylamino)-2',6'-acetoxylidide - 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide - 2-Diethylamino-2',6'-acetoxylidide - Cuivasil - Duncaine - Duncaine - LIDOCAINE - Leostesin - Leostesin - Lidothesin - Lignocaine - Lignocaine - Omega-diethylamino-2,6-dimethylacetanilide - Rucaina - Rucaina - lidocaine