Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7

**Semantic type:** Neoplastic Process

**Definition:** Stage IVA includes: (T4a, N0, M0); (T4a, N1, M0); (T1, N2, M0); (T2, N2, M0); (T3, N2, M0); (T4a, N2, M0). T4a: Tumor with moderately advanced local disease. Tumor invades the larynx, extrinsic muscle of tongue, medial pterygoid, hard palate, or mandible. Mucosal extension to lingual surface of epiglottis from primary tumors of the base of the tongue and vallecula does not constitute invasion of larynx. T1: Tumor 2 cm or less in greatest dimension. T2: Tumor more than 2 cm but not more than 4 cm in greatest dimension. T3: Tumor measuring more than 4 centimeters in greatest dimension or extension to lingual surface of epiglottis. N0: No regional lymph node metastasis. N1: Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension. N2: Tumor with metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension, or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension, or in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. M0: No distant metastasis. (AJCC 7th ed.)

**Synonyms:** - Stage IVA Epidermoid Carcinoma of Oropharynx - Stage IVA Epidermoid Carcinoma of the Oropharynx - Stage IVA Oropharyngeal Epidermoid Carcinoma - Stage IVA Oropharyngeal Squamous Cell Carcinoma - Stage IVA Oropharyngeal Throat Squamous Cell Cancer - Stage IVA Oropharynx Epidermoid Carcinoma - Stage IVA Oropharynx Squamous Cell Carcinoma - Stage IVA Squamous Cell Carcinoma of Oropharynx - Stage IVA Squamous Cell Carcinoma of the Oropharynx